Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions

can i drink alcohol while taking levofloxacin

They may experience side effects due to the increased tyramine levels, rather than the alcohol itself. Although data are not optimal, it is reasonable to advise avoidance of alcohol consumption in patients taking isoniazid. A disulfiram-like reaction and a possible increased risk of hepatitis are potential concerns. Linezolid is a weak, nonspecific inhibitor of monoamine oxidase (MAO) enzymes (81). Studies have shown positive pressor responses in comparison with placebo with tyramine administration (81, 82). One patient developed heart block after taking linezolid and 7 mg of tyramine (81, 82).

It’s important to check with your doctor or pharmacist before you mix alcohol with an antibiotic as this might be dangerous for your liver or cause other reactions. Should you experience any serious side effects or reactions listed or not listed, seek immediate medical attention. When levoFLOXacin as the oral solution is given with enteral (tube) feedings, levoFLOXacin may not work as well. You could interrupt the feeding for 1 hour before and 2 hours after the levoFLOXacin dose.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. There are 2 alcohol/food/lifestyle interactions with levofloxacin. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements. Before you have any medical tests, tell the medical doctor in charge that you are using this medicine. If you have a severe reaction from the sun, check with your doctor.

Why Should You Avoid Drinking Alcohol While Taking Antibiotics?

can i drink alcohol while taking levofloxacin

Alcohol did not impact the PK of ceftriaxone in a rat pneumonia model (13). Acute alcohol exposure increased the biliary excretion of cefadroxil and decreased the urinary excretion and absorption of cephalexin. Chronic alcohol exposure had no significant effect on absorption kinetics or biliary or urinary excretion for either of these antibiotics (14).

  1. People deficient in folic acid may be at risk of further reducing their folic acid levels while taking trimethoprim-sulfamethoxazole.
  2. If your doctor tells you that you shouldn’t drink alcohol, ask how long you should wait before drinking again.
  3. Antibiotics are among the most commonly prescribed medications in the outpatient setting (2).
  4. This can cause dangerous side effects or make them less effective at removing bacteria.
  5. If you have low blood potassium or an abnormally slow heartbeat, levofloxacin may increase your risk of having a fast, slow, or irregular heartbeat, loss of consciousness, or fainting spells.

Levofloxacin and Alcohol/Food Interactions

Also, the antibiotic linezolid (Zyvox) interacts with some alcoholic drinks, including red wine and tap beer. Drinking these with this medicine can cause a harmful rise in blood pressure. A few antibiotics should not be mixed with any amount of alcohol. These include metronidazole (Flagyl), tinidazole (Tindamax) and sulfamethoxazole-trimethoprim (Bactrim, Septra). Drinking alcohol with these medicines can cause side effects such as flushing, headache, nausea and vomiting, and fast heart rate. See the Drugs.com Drug Interactions Checker to review drug combinations which may lead to serious interactions.

What Should I Avoid Eating and Drinking With Levaquin?

Daily alcohol consumption can also overwhelm your liver, potentially interfering with Levofloxacin’s effectiveness and harming your liver. It’s crucial to listen to the medical advice and refrain from combining Levofloxacin and alcohol to ensure effective treatment and avoid potential complications. If you experience side effects or reactions, what is tom arnold doing now seek immediate medical attention. The articles were chosen after a search of published English language medical literature. A secondary search was performed via review of references found from the initial search. All randomized controlled trials and results from smaller, nonrandomized, open-label studies were included, provided that the studies had adequate methodology as judged by the authors.

Frequent alcohol use can also weaken your immune system, making it easier to pick up contagious illnesses. Use of alcohol with griseofulvin should be avoided due to risk of a disulfiram-like reaction, which may be severe. Per package labeling, alcohol did not affect alcohol dehydrogenase in in vitro studies and may be concurrently consumed with secnidazole (73). Alcohol may adversely affect the PK of erythromycin and may increase blood alcohol levels. Data are limited regarding the adverse effects of concomitant use of FQs and alcohol.

While these medications aren’t appropriate for every illness, they’re effective for treating certain infections. Just a few days of antibiotics can wipe out uncomfortable or painful illnesses or infections. First-line treatment of pulmonary tuberculosis (TB) involves an initial phase of four agents (isoniazid, pyrazinamide, ethambutol, and rifampin) (98). Treatment is prolonged, with agents known to be hepatotoxic (98). Multidrug-resistant tuberculosis has necessitated the use of second-line agents, which can result in adverse neurological reactions, making concomitant use with alcohol undesirable (99). The use of alcohol with griseofulvin is not recommended by the National Consumers League, the FDA, or the NIH (4, 5).

In addition, alcohol can worsen the side-effects that Levaquin causes. This can include an excessive amount of light-headedness and giddiness. Everlywell offers health and wellness solutions including laboratory testing for wellness monitoring, informational and educational use.

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